Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) Peptide
Quick Overview for Splicing Factor 3b, Subunit 1, 155kDa (SF3B1) Peptide (ABIN938085)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- ERLDPFADGG KTPDPKMNAR TYMDVMREQH LTKEEREIRQ QLAEKAKAGE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SF3 B1 antibody,
Alternative Names: SF3B1 control peptide, SF3B1 antibody Blocking Peptide, Anti-SF3B1 Blocking Peptide, Splicing Factor 3B Subunit 1 155Kda Blocking Peptide, SF3B1, SFB1-3, SFB1 3, SFB1-3 Blocking Peptide, SFB1 3 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
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Background
- SF3B1 is subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures.
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Molecular Weight
- 87 kDa
Target
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