Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) Peptide
CYP1A1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938330
Quick Overview for Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) Peptide (ABIN938330)
Target
CYP1A1
(Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- FKDLNEKFYS FMQKMVKEHY KTFEKGHIRD ITDSLIEHCQ EKQLDENANV
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of CYP1 A1 antibody,
Alternative Names: CYP1A1 control peptide, CYP1A1 antibody Blocking Peptide, Anti-CYP1A1 Blocking Peptide, Cytochrome P450 Family 1 Subfamily A Polypeptide 1 Blocking Peptide, AHH Blocking Peptide, AHRR Blocking Peptide, CP11 Blocking Peptide, CYP1 Blocking Peptide, P1-450 Blocking Peptide, P450-C Blocking Peptide, P450DX Blocking Peptide, CYP1A1, CYPA-1, CYPA 1, CYPA-1 Blocking Peptide, CYPA 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- CYP1A1 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1))
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Background
- CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 has been associated with lung cancer risk.
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Molecular Weight
- 58 kDa
Target
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