24-Dehydrocholesterol Reductase (DHCR24) Peptide
DHCR24
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all Seladin 1 (DHCR24) products
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- FLLPLSLIFD IYYYVRAWVV FKLSSAPRLH EQRVRDIQKQ VREWKEQGSK
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of DHCR24 antibody,
Alternative Names: DHCR24 control peptide, DHCR24 antibody Blocking Peptide, Anti-DHCR24 Blocking Peptide, 24-Dehydrocholesterol Reductase Blocking Peptide, KIAA0018 Blocking Peptide, Nbla03646 Blocking Peptide, SELADIN1 Blocking Peptide, seladin-1 Blocking Peptide, DHCR24, DHCR-24, DHCR 24, DHCR-24 Blocking Peptide, DHCR 24 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
- Background
- DHCR24 is a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.
- Molecular Weight
- 58 kDa
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