E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) Peptide
SIAH1
Reactivity: Mammalian
Host: Synthetic
BP, IHC, WB
Catalog No. ABIN938472
Quick Overview for E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) Peptide (ABIN938472)
Target
SIAH1
(E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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Peptide Type
- Synthetic
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Sequence
- FTCLPAARTR KRKEMSRQTA TALPTGTSKC PPSQRVPALT GTTASNNDLA
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SIAH1 antibody,
Alternative Names: SIAH1 control peptide, SIAH1 antibody Blocking Peptide, Anti-SIAH1 Blocking Peptide, seven in absentia homolog 1, Drosophila Blocking Peptide, SIAH1, SIAH-1, SIAH 1, SIAH-1 Blocking Peptide, SIAH 1 Blocking Peptide
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E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1) peptide
SIAH1 Reactivity: Human, Rat, Cow, Dog, Mouse Host: Synthetic BP, Imm
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- SIAH1 (E3 Ubiquitin-Protein Ligase SIAH1 (SIAH1))
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Background
- SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
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Molecular Weight
- 35 kDa
Target
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