Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Peptide
Quick Overview for Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Peptide (ABIN938719)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- GILEGICGTV HDEKKPDVLL YDTIFQIFNN RNCLSLKDKP KVIIVQACRG
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of CASP4 antibody,
Alternative Names: CASP4 control peptide, CASP4 antibody Blocking Peptide, Anti-CASP4 Blocking Peptide, caspase 4, apoptosis-related cysteine peptidase Blocking Peptide, ICE(rel)II Blocking Peptide, ICEREL-II Blocking Peptide, ICH-2 Blocking Peptide, Mih1/TX Blocking Peptide, TX Blocking Peptide, CASP4, CASP-4, CASP 4, CASP-4 Blocking Peptide, CASP 4 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
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Background
- This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
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Molecular Weight
- 10 kDa
Target
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