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Cathepsin E (CTSE) Peptide

CTSE Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN938721

Quick Overview for Cathepsin E (CTSE) Peptide (ABIN938721)

Target

Cathepsin E (CTSE)

Origin

Mammalian

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    GILGLGYPSL AVGGVTPVFD NMMAQNLVDL PMFSVYMSSN PEGGAGSELI

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of CTSE antibody,
    Alternative Names: CTSE control peptide, CTSE antibody Blocking Peptide, Anti-CTSE Blocking Peptide, cathepsin E Blocking Peptide, CATE Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    Cathepsin E (CTSE)

    Background

    The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.

    Molecular Weight

    40 kDa
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