Inhibin, alpha (INHA) Peptide
INHA
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938770
Quick Overview for Inhibin, alpha (INHA) Peptide (ABIN938770)
Target
Inhibin alpha (INHA)
(Inhibin, alpha (INHA))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GLAQEAEEGL FRYMFRPSQH TRSRQVTSAQ LWFHTGLDRQ GTAASNSSEP
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of INHA antibody,
Alternative Names: Inhibin Alpha control peptide, Inhibin Alpha antibody Blocking Peptide, Anti-Inhibin Alpha Blocking Peptide, INHA Blocking Peptide -
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Inhibin alpha (INHA) (Inhibin, alpha (INHA))
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Background
- INHA joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
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Molecular Weight
- 40 kDa
Target
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