Collagen, Type I, alpha 1 (COL1A1) Peptide
COL1A1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938780
Quick Overview for Collagen, Type I, alpha 1 (COL1A1) Peptide (ABIN938780)
Target
COL1A1
(Collagen, Type I, alpha 1 (COL1A1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GLGRQVYDPK YCAAPTEPVI HNGSQGTGTN GSEISDSDYQ AEYPDEYHGE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of COL1 A1 antibody,
Alternative Names: COL1A1 control peptide, COL1A1 antibody Blocking Peptide, Anti-COL1A1 Blocking Peptide, collagen, type I, alpha 1 Blocking Peptide, OI4 Blocking Peptide, COL1A1, COLA-1, COLA 1, COLA-1 Blocking Peptide, COLA 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- COL1A1 (Collagen, Type I, alpha 1 (COL1A1))
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Background
- This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
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Molecular Weight
- 36 kDa
Target
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