Importin 5 (IPO5) Peptide
IPO5
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN938839
Quick Overview for Importin 5 (IPO5) Peptide (ABIN938839)
Target
Importin 5 (IPO5)
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GNNQWPEGLK FLFDSVSSQN VGLREAALHI FWNFPGIFGN QQQHYLDVIK
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of RANBP5 antibody,
Alternative Names: RANBP5 control peptide, RANBP5 antibody Blocking Peptide, Anti-RANBP5 Blocking Peptide, importin 5 Blocking Peptide, DKFZp686O1576 Blocking Peptide, FLJ43041 Blocking Peptide, IMB3 Blocking Peptide, KPNB3 Blocking Peptide, MGC2068 Blocking Peptide, RANBP5 Blocking Peptide, RANBP5, RANBP-5, RANBP 5, RANBP-5 Blocking Peptide, RANBP 5 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Importin 5 (IPO5)
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Background
- Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate.
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Molecular Weight
- 125 kDa
Target
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