Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2) Peptide
HLA-DQA2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939034
Quick Overview for Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2) Peptide (ABIN939034)
Target
HLA-DQA2
(Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- GVNFYQSHGP SGQYTHEFDG DEEFYVDLET KETVWQLPMF SKFISFDPQS
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of HLA-DQA2 antibody,
Alternative Names: HLA-DQA2 control peptide, HLA-DQA2 antibody Blocking Peptide, Anti-HLA-DQA2 Blocking Peptide, Major Histocompatibility Complex Class Ii Dq Alpha 2 Blocking Peptide, DQ alpha Blocking Peptide, HLA-DXA Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- HLA-DQA2 (Major Histocompatibility Complex, Class II, DQ alpha 2 (HLA-DQA2))
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Background
- This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognised by CD4 T-cells.
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Molecular Weight
- 28 kDa
Target
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