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Synovial Sarcoma, X Breakpoint 2 (SSX2) Peptide

SSX2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN939235

Quick Overview for Synovial Sarcoma, X Breakpoint 2 (SSX2) Peptide (ABIN939235)

Target

SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Origin

Mammalian

Source

  • 2
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    HRWSSQNTHN IGRFSLSTSM GAVHGTPKTI THNRDPKGGN MPGPTDCVRE

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of SSX2 antibody,
    Alternative Names: SSX2 control peptide, SSX2 antibody Blocking Peptide, Anti-SSX2 Blocking Peptide, synovial sarcoma, X breakpoint 2 Blocking Peptide, HD21 Blocking Peptide, HOM-MEL-40 Blocking Peptide, MGC119055 Blocking Peptide, MGC15364 Blocking Peptide, MGC3884 Blocking Peptide, SSX Blocking Peptide, SSX2, SSX-2, SSX 2, SSX-2 Blocking Peptide, SSX 2 Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

    Background

    SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

    Molecular Weight

    25 kDa
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