Kelch-Like ECH-Associated Protein 1 (KEAP1) Peptide
Quick Overview for Kelch-Like ECH-Associated Protein 1 (KEAP1) Peptide (ABIN939247)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- HTFLDSVECY DPDTDTWSEV TRMTSGRSGV GVAVTMEPCR KQIDQQNCTC
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of KEAP1 antibody,
Alternative Names: KEAP1 control peptide, KEAP1 antibody Blocking Peptide, Anti-KEAP1 Blocking Peptide, kelch-like ECH-associated protein 1 Blocking Peptide, KEAP1, KEAP-1, KEAP 1, KEAP-1 Blocking Peptide, KEAP 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
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Background
- KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
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Molecular Weight
- 70 kDa
Target
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