alpha-Methylacyl-CoA Racemase (AMACR) Peptide
AMACR
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939342
Quick Overview for alpha-Methylacyl-CoA Racemase (AMACR) Peptide (ABIN939342)
Target
AMACR
(alpha-Methylacyl-CoA Racemase (AMACR))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- IFDGTDACVT PVLTFEEVVH HDHNKERGSF ITSEEQDVSP RPAPLLLNTP
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of AMACR antibody,
Alternative Names: AMACR control peptide, AMACR antibody Blocking Peptide, Anti-AMACR Blocking Peptide, alpha-methylacyl-CoA racemase Blocking Peptide, CBAS4 Blocking Peptide, RACE Blocking Peptide, RM Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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Background
- This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
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Molecular Weight
- 42 kDa
Target
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