Metalloproteinase Inhibitor 2 (TIMP2) Peptide
TIMP2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939590
Quick Overview for Metalloproteinase Inhibitor 2 (TIMP2) Peptide (ABIN939590)
Target
TIMP2
(Metalloproteinase Inhibitor 2 (TIMP2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- IVPWDTLSTT QKKSLNHRYQ MGCECKITRC PMIPCYISSP DECLWMDWVT
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TIMP2 antibody,
Alternative Names: TIMP2 control peptide, TIMP2 antibody Blocking Peptide, Anti-TIMP2 Blocking Peptide, TIMP metallopeptidase inhibitor 2 Blocking Peptide, CSC-21K Blocking Peptide, TIMP2, TIMP-2, TIMP 2, TIMP-2 Blocking Peptide, TIMP 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
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Background
- This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
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Molecular Weight
- 22 kDa
Target
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