RAN Binding Protein 1 (RANBP1) Peptide
RANBP1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN939753
Quick Overview for RAN Binding Protein 1 (RANBP1) Peptide (ABIN939753)
Target
RANBP1
(RAN Binding Protein 1 (RANBP1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KFEECRKEIE EREKKAGSGK NDHAEKVAEK LEALSVKEET KEDAEEKQ
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of RANBP1 antibody,
Alternative Names: RanBP1 control peptide, RanBP1 antibody Blocking Peptide, Anti-RanBP1 Blocking Peptide, Ran Binding Protein 1 Blocking Peptide, MGC88701 Blocking Peptide, RanBP1, RanBP-1, RanBP 1, RanBP-1 Blocking Peptide, RanBP 1 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- RANBP1 (RAN Binding Protein 1 (RANBP1))
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Background
- Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23 kDa protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92 % similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
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Molecular Weight
- 23 kDa
Target
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