Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2) Peptide
Quick Overview for Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2) Peptide (ABIN939809)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- KHTESLKPAA TRLPARAAWF LQELPSFAVP AGILARQPLS LFGPPGTVLL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SRD5 A2 antibody,
Alternative Names: SRD5A2 control peptide, SRD5A2 antibody Blocking Peptide, Anti-SRD5A2 Blocking Peptide, Steroid-5-Alpha-Reductase Alpha Polypeptide 2 Blocking Peptide, 3-Oxo-5 Alpha-Steroid Delta 4-Dehydrogenase Alpha 2 Blocking Peptide, MGC138457 Blocking Peptide, SRD5A2, SRDA2-5, SRDA2 5, SRDA2-5 Blocking Peptide, SRDA2 5 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- SRD5A2 (Steroid-5-alpha-Reductase, alpha Polypeptide 2 (3-Oxo-5 alpha-Steroid delta 4-Dehydrogenase alpha 2) (SRD5A2))
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Background
- This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).
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Molecular Weight
- 28 kDa
Target
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