Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) Peptide
PCSK2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940185
Quick Overview for Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) Peptide (ABIN940185)
Target
PCSK2
(Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- LASTFSNGRK RNPEAGVATT DLYGNCTLRH SGTSAAAPEA AGVFALALEA
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of PCSK2 antibody,
Alternative Names: PCSK2 control peptide, PCSK2 antibody Blocking Peptide, Anti-PCSK2 Blocking Peptide, proprotein convertase subtilisin/kexin type 2 Blocking Peptide, NEC2 Blocking Peptide, PC2 Blocking Peptide, SPC2 Blocking Peptide, PCSK2, PCSK-2, PCSK 2, PCSK-2 Blocking Peptide, PCSK 2 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))
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Background
- This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Molecular Weight
- 58 kDa
Target
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