Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) Peptide
SIGLEC12
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940221
Quick Overview for Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12) Peptide (ABIN940221)
Target
SIGLEC12
(Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- LCVSVLCSFS YPQNGWTASD PVHGYWFRAG DHVSRNIPVA TNNPARAVQE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of SIGLEC12 antibody,
Alternative Names: SIGLEC12 control peptide, SIGLEC12 antibody Blocking Peptide, Anti-SIGLEC12 Blocking Peptide, Sialic Acid Binding Ig-Like Lectin 12 Blocking Peptide, FLJ38600 Blocking Peptide, S2V Blocking Peptide, SIGLECL1 Blocking Peptide, SLG Blocking Peptide, Siglec-12 Blocking Peptide, Siglec-L1 Blocking Peptide, Siglec-XII Blocking Peptide, SIGLEC12, SIGLEC-12, SIGLEC 12, SIGLEC-12 Blocking Peptide, SIGLEC 12 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- SIGLEC12 (Sialic Acid Binding Ig-Like Lectin 12 (SIGLEC12))
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Background
- Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. SIGLEC12 is a member of the SIGLEC3-like subfamily of SIGLECs. SIGLEC12, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2.
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Molecular Weight
- 63 kDa
Target
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