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CD27 Molecule (CD27) Peptide

CD27 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN940410

Quick Overview for CD27 Molecule (CD27) Peptide (ABIN940410)

Target

CD27 (CD27 Molecule (CD27))

Origin

Mammalian

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Peptide Type

    Synthetic

    Sequence

    LHQRRKYRSN KGESPVEPAE PCRYSCPREE EGSTIPIQED YRKPEPACSP

    Characteristics

    A synthetic peptide for use as a blocking control in assays to test for specificity of CD27 antibody,
    Alternative Names: CD27 control peptide, CD27 antibody Blocking Peptide, Anti-CD27 Blocking Peptide, CD27 molecule Blocking Peptide, MGC20393 Blocking Peptide, S152 Blocking Peptide, T14 Blocking Peptide, TNFRSF7 Blocking Peptide, Tp55 Blocking Peptide, CD27, CD-27, CD 27, CD-27 Blocking Peptide, CD 27 Blocking Peptide
  • Application Notes

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handling Advice

    Avoid repeated freeze/thaw cycles.

    Storage

    -20 °C

    Storage Comment

    Store at -20 °C long term.
  • Target

    CD27 (CD27 Molecule (CD27))

    Background

    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

    Molecular Weight

    27 kDa
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