Transcription Elongation Factor A (SII), 3 (TCEA3) Peptide
Quick Overview for Transcription Elongation Factor A (SII), 3 (TCEA3) Peptide (ABIN940465)
Target
Origin
Source
Application
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Peptide Type
- Synthetic
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Sequence
- LKDPRNPGLR RNVLSGAISP ELIAKMTAEE MASDELRELR NAMTQEAIRE
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of Tcea3 antibody,
Alternative Names: Tcea3 control peptide, Tcea3 antibody Blocking Peptide, Anti-Tcea3 Blocking Peptide, transcription elongation factor A, SII, 3 Blocking Peptide, S-II Blocking Peptide, SII-K1 Blocking Peptide, Tcea3, Tcea-3, Tcea 3, Tcea-3 Blocking Peptide, Tcea 3 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- TCEA3 (Transcription Elongation Factor A (SII), 3 (TCEA3))
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Background
- Tcea3 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
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Molecular Weight
- 39 kDa
Target
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