TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp) Peptide
Tiparp
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940493
Quick Overview for TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp) Peptide (ABIN940493)
Target
Tiparp
(TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- LKTCFKKKDQ KRLGTGTLRS LRPILNTLLE SGSLDGVFRS RNQSTDENSL
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TIPARP antibody,
Alternative Names: TIPARP control peptide, TIPARP antibody Blocking Peptide, Anti-TIPARP Blocking Peptide, Tcdd-Inducible Poly Blocking Peptide, Adp-Ribose Polymerase Blocking Peptide, DDF1 Blocking Peptide, DKFZP434J214 Blocking Peptide, DKFZp686N0351 Blocking Peptide, DKFZp686P1838 Blocking Peptide, FLJ40466 Blocking Peptide, PARP-1 Blocking Peptide, PARP-7 Blocking Peptide, PARP7 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- Tiparp (TCDD-Inducible Poly(ADP-Ribose) Polymerase (Tiparp))
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Background
- TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor, repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.
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Molecular Weight
- 76 kDa
Target
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