SH3 Domain Containing Ring Finger 1 (SH3RF1) Peptide
SH3RF1
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940541
Quick Overview for SH3 Domain Containing Ring Finger 1 (SH3RF1) Peptide (ABIN940541)
Target
SH3RF1
(SH3 Domain Containing Ring Finger 1 (SH3RF1))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
Peptide Type
- Synthetic
-
Sequence
- LLKLLSGAST KRKPRVSPPA SPTLEVELGS AELPLQGAVG PELPPGGGHG
-
Characteristics
-
A synthetic peptide for use as a blocking control in assays to test for specificity of SH3 RF1 antibody,
Alternative Names: SH3RF1 control peptide, SH3RF1 antibody Blocking Peptide, Anti-SH3RF1 Blocking Peptide, Sh3 Domain Containing Ring Finger 1 Blocking Peptide, FLJ21602 Blocking Peptide, KIAA1494 Blocking Peptide, POSH Blocking Peptide, RNF142 Blocking Peptide, SH3MD2 Blocking Peptide, SH3RF1, SHRF1-3, SHRF1 3, SHRF1-3 Blocking Peptide, SHRF1 3 Blocking Peptide
-
-
-
-
Application Notes
- Optimal conditions should be determined by the investigator
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
Buffer
- PBS
-
Handling Advice
- Avoid repeated freeze/thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20 °C long term.
-
-
- SH3RF1 (SH3 Domain Containing Ring Finger 1 (SH3RF1))
-
Background
- SH3RF1 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3RF1 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane.
-
Molecular Weight
- 93 kDa
Target
-
You are here:
