AP2 associated kinase 1 (AAK1) (C-Term) Peptide
AAK1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN972704
Quick Overview for AP2 associated kinase 1 (AAK1) (C-Term) Peptide (ABIN972704)
Target
AAK1
(AP2 associated kinase 1 (AAK1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- SGFDVPEGSD KVAEDEFDPI PVLITKNPQG GHSRNSSGSS ESSLPNLARS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AAK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AAK1 (AP2 associated kinase 1 (AAK1))
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Background
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Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Alias Symbols: DKFZp686F03202, DKFZp686K16132, FLJ23712, FLJ25931, FLJ31060, FLJ42882, FLJ45252, KIAA1048, MGC138170, MGC164568, MGC164570
Protein Size: 961 -
Molecular Weight
- 104 kDa
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Gene ID
- 22848
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NCBI Accession
- NM_014911, NP_055726
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UniProt
- Q2M2I8
Target
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