ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1) Peptide
Quick Overview for ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1) Peptide (ABIN972742)
Target
Origin
Source
Application
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ABCE1 antibody (Catalog #: ARP43633_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ABCE1 (ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))
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Background
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ABCE1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I
Protein Interaction Partner: RNASE2,RNASEL,EIF3F,EIF3H,RNASEL,USP50
Protein Size: 599 -
Molecular Weight
- 67 kDa
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Gene ID
- 6059
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NCBI Accession
- NM_001040876, NP_001035809
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UniProt
- P61221
Target
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