Acetyl-CoA Acetyltransferase 1 (ACAT1) (Middle Region) Peptide
ACAT1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Quick Overview for Acetyl-CoA Acetyltransferase 1 (ACAT1) (Middle Region) Peptide (ABIN972786)
Target
ACAT1
(Acetyl-CoA Acetyltransferase 1 (ACAT1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- Middle Region
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Sequence
- GHQDVMVAGG MESMSNVPYV MNRGSTPYGG VKLEDLIVKD GLTDVYNKIH
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ACAT1 Antibody(ARP54277_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ACAT1 (Acetyl-CoA Acetyltransferase 1 (ACAT1))
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Background
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ACAT1 is a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. The gene encoding ACAT1 spans approximately 27 kb and contains 12 exons interrupted by 11 introns. Defects in this gene are associated with the alpha-methylacetoaceticaciduria disorder, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
Alias Symbols: ACAT, MAT, T2, THIL
Protein Interaction Partner: EIF1B
Protein Size: 427 -
Molecular Weight
- 41 kDa
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Gene ID
- 38
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NCBI Accession
- NM_000019, NP_000010
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UniProt
- P24752
Target
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