Adenosine Deaminase (ADA) (Middle Region) Peptide
Quick Overview for Adenosine Deaminase (ADA) (Middle Region) Peptide (ABIN972891)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ADA antibody (Catalog #: ARP51758_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ADA (Adenosine Deaminase (ADA))
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Background
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ADA is an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: ADORA1,ADORA2A,ADORA2B,DPP4,DRD1,GRB2,NR3C1,ADORA1,ADORA2A,DRD1,NR3C1
Protein Size: 363 -
Molecular Weight
- 41 kDa
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Gene ID
- 100
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NCBI Accession
- NM_000022, NP_000013
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UniProt
- P00813
Target
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