ADAM Metallopeptidase Domain 12 (ADAM12) (N-Term) Peptide
Quick Overview for ADAM Metallopeptidase Domain 12 (ADAM12) (N-Term) Peptide (ABIN972894)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ADAM12 antibody (Catalog #: ARP41334_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))
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Background
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ADAM12 is a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM12 gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.
Alias Symbols: MCMP, MCMPMltna, MLTN, MLTNA
Protein Interaction Partner: ACTN2,EGF,FSTL3,GRB2,IGFBP3,IGFBP5,PACSIN3,PIK3R1,SH3D19,SRC,YES1,ACTN2,IGFBP3,IGFBP5,PIK3R1,SH3D19,SH3D19
Protein Size: 738 -
Molecular Weight
- 58 kDa
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Gene ID
- 8038
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NCBI Accession
- NM_021641, NP_067673
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UniProt
- O43184
Target
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