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ADAM Metallopeptidase Domain 12 (ADAM12) (N-Term) Peptide

ADAM12 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN972894

Quick Overview for ADAM Metallopeptidase Domain 12 (ADAM12) (N-Term) Peptide (ABIN972894)

Target

ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))

Origin

Human

Source

  • 8
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-ADAM12 antibody (Catalog #: ARP41334_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))

    Background

    ADAM12 is a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM12 gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis.

    Alias Symbols: MCMP, MCMPMltna, MLTN, MLTNA

    Protein Interaction Partner: ACTN2,EGF,FSTL3,GRB2,IGFBP3,IGFBP5,PACSIN3,PIK3R1,SH3D19,SRC,YES1,ACTN2,IGFBP3,IGFBP5,PIK3R1,SH3D19,SH3D19

    Protein Size: 738

    Molecular Weight

    58 kDa

    Gene ID

    8038

    NCBI Accession

    NM_021641, NP_067673

    UniProt

    O43184
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