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Adducin 3 (Gamma) (ADD3) (Middle Region) Peptide

ADD3 Reactivity: Human Host: Synthetic BP, WB, ICC

Catalog No. ABIN972932

Quick Overview for Adducin 3 (Gamma) (ADD3) (Middle Region) Peptide (ABIN972932)

Target

ADD3 (Adducin 3 (Gamma) (ADD3))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunocytochemistry (ICC)

Protein Region

Middle Region

Sequence

AYYDYQGSLE EQEERIQLQK VLGPSCKVLV LRNHGVVALG ETLEEAFHYI

Characteristics

This is a synthetic peptide designed for use in combination with anti-ADD3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

Purification

Purified
Adducin 3 (Gamma) (ADD3) peptide
ADD3 Reactivity: Mammalian Host: Synthetic BP, WB, IHC

Adducin 3 (Gamma) (ADD3) peptide
ADD3 Reactivity: Mammalian Host: Synthetic BP, WB, IHC

Adducin 3 (Gamma) (ADD3) (C-Term) peptide
ADD3 Reactivity: Human Host: Synthetic BP, WB, ICC

Adducin 3 (Gamma) (ADD3) peptide
ADD3 Reactivity: Human, Cow, Mouse, Rat Host: Synthetic BP

Application Notes

Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

Concentration

1 mg/mL

Buffer

Final peptide concentration is 1 mg/mL in PBS.

Handling Advice

Avoid repeated freeze-thaw cycles.

Storage

-20 °C

Storage Comment

For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target

ADD3 (Adducin 3 (Gamma) (ADD3))

Background

Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains.

Alias Symbols: ADDL

Protein Interaction Partner: PRKCA

Protein Size: 706

Molecular Weight

78 kDa

Gene ID

120

NCBI Accession

NM_016824, NP_058432

UniProt

Q9UEY8

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