Adrenergic, beta-1-, Receptor (ADRB1) (Middle Region) Peptide
ADRB1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN972963
Quick Overview for Adrenergic, beta-1-, Receptor (ADRB1) (Middle Region) Peptide (ABIN972963)
Target
ADRB1
(Adrenergic, beta-1-, Receptor (ADRB1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ADRB1 antibody (Catalog #: ARP36551_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Adrenergic, beta-1-, Receptor (ADRB1) peptide
ADRB1 Reactivity: Human, Rat, Dog, Mouse Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
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Background
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The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in ADRB1 gene have been shown to affect the resting heart rate and can be involved in heart failure.The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADRB1R, B1AR, BETA1AR, RHR
Protein Interaction Partner: ADRA2A,GIPC1,GPRASP1,GPRASP2,GRB2,SH3GL2,SH3GL3,ADRA2A,ARRB1,DLG1,DLG4,DLGAP2,GIPC1,GOPC,GPRASP1,GPRASP2,GRB2,MAGI2,MAGI3,NOS1,SH3GL2,SH3GL3,ARRB1,DLG4,GIPC1
Protein Size: 477 -
Molecular Weight
- 51 kDa
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Gene ID
- 153
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NCBI Accession
- NM_000684, NP_000675
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UniProt
- P08588
Target
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