A Kinase (PRKA) Anchor Protein 10 (AKAP10) (Middle Region) Peptide
AKAP10
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973054
Quick Overview for A Kinase (PRKA) Anchor Protein 10 (AKAP10) (Middle Region) Peptide (ABIN973054)
Target
AKAP10
(A Kinase (PRKA) Anchor Protein 10 (AKAP10))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- ESLYQRTYAG KMTFGRVSDL GQFIRESEPE PDVRKSKGSM FSQAMKKWVQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AKAP10 Antibody(ARP36326_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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A Kinase (PRKA) Anchor Protein 10 (AKAP10) peptide
AKAP10 Reactivity: Human, Rat, Mouse, Dog Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))
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Background
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA, therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.
Alias Symbols: D-AKAP2, MGC9414, PRKA10
Protein Interaction Partner: PDZK1,PRKAR1A,PRKAR2A,PRKAR2B,SLC9A3R1,PDZK1,PRKAR1A
Protein Size: 662 -
Molecular Weight
- 71 kDa
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Gene ID
- 11216
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NCBI Accession
- NM_007202, NP_009133
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UniProt
- O43572
Target
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