A Kinase (PRKA) Anchor Protein 8 (AKAP8) (Middle Region) Peptide
AKAP8
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973062
Quick Overview for A Kinase (PRKA) Anchor Protein 8 (AKAP8) (Middle Region) Peptide (ABIN973062)
Target
AKAP8
(A Kinase (PRKA) Anchor Protein 8 (AKAP8))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AKAP8 antibody (Catalog #: ARP32754_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))
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Background
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP8 is a member of the AKAP family. It is located in the nucleus during interphase and is distinctly redistributed during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA.The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is located in the nucleus during interphase and is distinctly redistributed during mitosis. This protein has a cell cycle-dependent interaction with the RII subunit of PKA. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AKAP95, DKFZp586B1222, AKAP-8, AKAP 95, AKAP-95
Protein Interaction Partner: AMY1C,CASP3,CCND1,CCND2,CCND3,DDX5,MCM2,PRKAR2A,RELA,AMY1A,CCND1,CCND2,CCND3,DDX5,MCM2,PRKAR2A
Protein Size: 692 -
Molecular Weight
- 76 kDa
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Gene ID
- 10270
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NCBI Accession
- NM_005858, NP_005849
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UniProt
- O43823
Target
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