Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) (N-Term) Peptide
AKR1B1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973070
Quick Overview for Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) (N-Term) Peptide (ABIN973070)
Target
AKR1B1
(Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AKR1B1 antibody (Catalog #: ARP48179_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1) peptide
AKR1B1 Reactivity: Human, Mouse, Rat, Cow, Dog, Pig Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
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Background
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AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. There are a few putative pseudogenes for this gene, and one of them has been confirmed and mapped to chromosome 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADR, ALDR1, ALR2, AR, MGC1804
Protein Interaction Partner: SMAD1,TFE3
Protein Size: 316 -
Molecular Weight
- 36 kDa
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Gene ID
- 231
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NCBI Accession
- NM_001628, NP_001619
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UniProt
- P15121
Target
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