alpha-Methylacyl-CoA Racemase (AMACR) (Middle Region) Peptide
AMACR
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973163
Quick Overview for alpha-Methylacyl-CoA Racemase (AMACR) (Middle Region) Peptide (ABIN973163)
Target
AMACR
(alpha-Methylacyl-CoA Racemase (AMACR))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- SGENPYAPLN LLADFAGGGL MCALGIIMAL FDRTRTGKGQ VIDANMVEGT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AMACR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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Background
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This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Alias Symbols: CBAS4, RACE, RM, AMACRD
Protein Size: 394 -
Molecular Weight
- 43 kDa
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Gene ID
- 23600
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NCBI Accession
- NM_001167595, NP_001161067
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UniProt
- F8W9N1
Target
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