ADP-Ribosylation Factor 1 (ARF1) (Middle Region) Peptide
Quick Overview for ADP-Ribosylation Factor 1 (ARF1) (Middle Region) Peptide (ABIN973367)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ARF1 antibody (Catalog #: ARP48184_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ARF1 (ADP-Ribosylation Factor 1 (ARF1))
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Background
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ADP-ribosylation factor 1 (ARF1) is a member of the human ARF family. The family is composed of small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. These protein, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: -
Protein Interaction Partner: STAU1,AP1B1,AP1G1,AP3B1,AP3D1,AP4E1,AP4M1,ARF1,ARFGAP1,ARFIP1,ARFIP2,ARHGAP21,ASAP1,ASAP2,C4orf14,CHRM3,COPB1,COPE,COPG,CYTH1,CYTH2,EEF1G,GGA1,GGA2,GGA3,GOSR2,INSR,KDELR1,MDM4,NPM1,PICK1,PIP5K1A,PLD1,PLD2,PLEKHA8,PLIN2,RALA,TMED10,TMED2,WBP11,AP1B1,AP1G1,AP3S2,AP4E1,AP4M1,ARF1,ARFIP1,ARFIP2,C4orf14,CHRM3,COPB1,COPE,COPG,CYTH2,EEF1G,GCS1,GEA1,GGA1,GGA3,GLO3,KDELR1,OPRM1,PLD1,PLD2,RALA,WBP11
Protein Size: 181 -
Molecular Weight
- 21 kDa
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Gene ID
- 375
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NCBI Accession
- NM_001658, NP_001649
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UniProt
- P61204
Target
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