rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2) (C-Term) Peptide
ARHGEF2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN973401
Quick Overview for rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2) (C-Term) Peptide (ABIN973401)
Target
ARHGEF2
(rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- NTSPGVTANG EARTFNGSIE LCRADSDSSQ RDRNGNQLRS PQEEALQRLV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ARHGEF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))
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Background
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Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DKFZp547L106, DKFZp547P1516, FLJ45440, GEF, GEF-H1, GEFH1, KIAA0651, LFP40, P40
Protein Interaction Partner: CGN,CGN,PAK1,RAC1,RHOA,RRAS2,YWHAE,YWHAG,YWHAZ,MAPK1,MARK2,MYC,PAK1,PLCG1,RAC1,RHOA,TAF10,WASF1,YWHAQ
Protein Size: 986 -
Molecular Weight
- 111 kDa
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Gene ID
- 9181
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NCBI Accession
- NM_001162383, NP_001155855
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UniProt
- Q92974
Target
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