BH3 Interacting Domain Death Agonist (BID) (C-Term) Peptide
BID
Reactivity: Human
Host: Synthetic
BP, ICC, WB
Catalog No. ABIN973819
Quick Overview for BH3 Interacting Domain Death Agonist (BID) (C-Term) Peptide (ABIN973819)
Target
BID
(BH3 Interacting Domain Death Agonist (BID))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunocytochemistry (ICC), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LRNTSRSEED RNRDLATALE QLLQAYPRDM EKEKTMLVLA LLLAKKVASH
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-BID Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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BH3 Interacting Domain Death Agonist (BID) peptide
BID Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BID (BH3 Interacting Domain Death Agonist (BID))
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Background
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This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Alias Symbols: FP497, MGC15319, MGC42355
Protein Interaction Partner: BAX,BCL2,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L1,BCL2L2,BNC1,PACS2,BCL2L1,BAK1,BAX,BCL2,BCL2A1,BCL2L1,BCL2L2,BID,CAPN1,CASP1,CASP10,CASP2,CASP3,CASP8,CSNK1A1,CSNK1E,CSNK2A1,CSNK2A2,CSNK2B,GZMB,MCL1,YWHAB,ARHGDIA,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L2,BID,CAPN2,CASP10,
Protein Size: 241 -
Molecular Weight
- 27 kDa
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Gene ID
- 637
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NCBI Accession
- NM_197966, NP_932070
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UniProt
- B3KT21
Target
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