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Complement Component 1, Q Subcomponent, B Chain (C1QB) Peptide

C1QB Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN974149

Quick Overview for Complement Component 1, Q Subcomponent, B Chain (C1QB) Peptide (ABIN974149)

Target

C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))

Origin

Human

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-C1QB antibody (Catalog #: ARP44297_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))

    Background

    C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QB is the B-chain polypeptide of human complement subcomponent C1q.This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q.

    Alias Symbols: -

    Protein Interaction Partner: C1QA,C1QC,C1R,DEFA1,HRG,MYOC,PTX3

    Protein Size: 253

    Molecular Weight

    27 kDa

    Gene ID

    713

    NCBI Accession

    NM_000491, NP_000482

    UniProt

    P02746
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