GC-Rich Sequence DNA-Binding Factor 2 (GCFC2) (N-Term) Peptide
GCFC2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GCFC2 products
- GCFC2 (GC-Rich Sequence DNA-Binding Factor 2 (GCFC2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-C2orf3 antibody (Catalog #: ARP58090_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GCFC2 (GC-Rich Sequence DNA-Binding Factor 2 (GCFC2))
- Background
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The first mRNA transcript isolated for C2orf3 gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). C2orf3 belongs to the GCF family. It is a factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene.
Alias Symbols: DNABF, GCF, TCF9, C2orf3
Protein Interaction Partner: ATXN1
Protein Size: 781 - Molecular Weight
- 89 kDa
- Gene ID
- 6936
- NCBI Accession
- NM_003203, NP_003194
- UniProt
- P16383
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