GC-Rich Sequence DNA-Binding Factor 2 (GCFC2) (N-Term) Peptide
GCFC2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974215
Quick Overview for GC-Rich Sequence DNA-Binding Factor 2 (GCFC2) (N-Term) Peptide (ABIN974215)
Target
GCFC2
(GC-Rich Sequence DNA-Binding Factor 2 (GCFC2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-C2orf3 antibody (Catalog #: ARP58090_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GCFC2 (GC-Rich Sequence DNA-Binding Factor 2 (GCFC2))
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Background
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The first mRNA transcript isolated for C2orf3 gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). C2orf3 belongs to the GCF family. It is a factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene.
Alias Symbols: DNABF, GCF, TCF9, C2orf3
Protein Interaction Partner: ATXN1
Protein Size: 781 -
Molecular Weight
- 89 kDa
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Gene ID
- 6936
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NCBI Accession
- NM_003203, NP_003194
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UniProt
- P16383
Target
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