Capping Protein (Actin Filament) Muscle Z-Line, alpha 3 (CAPZA3) (N-Term) Peptide
CAPZA3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974458
Quick Overview for Capping Protein (Actin Filament) Muscle Z-Line, alpha 3 (CAPZA3) (N-Term) Peptide (ABIN974458)
Target
CAPZA3
(Capping Protein (Actin Filament) Muscle Z-Line, alpha 3 (CAPZA3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CAPZA3 antibody (Catalog #: ARP58604_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CAPZA3 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 3 (CAPZA3))
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Background
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F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CAPZA3 may play a role in the morphogenesis of spermatid.This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility.
Alias Symbols: CAPPA3, Gsg3
Protein Interaction Partner: ACTG1,CAPZA2
Protein Size: 299 -
Molecular Weight
- 33 kDa
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Gene ID
- 93661
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NCBI Accession
- NM_033328, NP_201585
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UniProt
- Q96KX2
Target
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