Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (Middle Region) Peptide
CASP6
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974477
Quick Overview for Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (Middle Region) Peptide (ABIN974477)
Target
Caspase 6 (CASP6)
(Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- QACRGNQHDV PVIPLDVVDN QTEKLDTNIT EVDAASVYTL PAGADFLMCY
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CASP6 Antibody(ARP58994_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
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Background
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This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
Alias Symbols: MCH2
Protein Interaction Partner: HTT,RB1,APP,CASP10,CASP3,CASP8,CFLAR,CHD3,DSP,EIF2S1,HTT,KRT18,LMNA,LMNB1,MAPT,NEDD4,NUAK1,PCYT1A,PPL,PRKCZ,PSEN1,PSEN2,PSME3,RB1,SATB1,SRF,SRP72,TFAP2A,TOP1,TRAF1,UBE4B,VIM,BIRC6,CASP10,CASP3,CASP6,CASP8,CHD3,TRAF1,XIAP
Protein Size: 293 -
Molecular Weight
- 11 kDa
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Gene ID
- 839
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NCBI Accession
- NM_001226, NP_001217
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UniProt
- P55212
Target
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