Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (N-Term) Peptide
CASP7
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974478
Quick Overview for Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (N-Term) Peptide (ABIN974478)
Target
Caspase 7 (CASP7)
(Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- NNKNFDKVTG MGVRNGTDKD AEALFKCFRS LGFDVIVYND CSCAKMQDLL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CASP7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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Background
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This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms.
Alias Symbols: CMH-1, ICE-LAP3, MCH3
Protein Interaction Partner: AR,ATN1,BIRC3,CTSG,GZMB,HTT,PARP1,PSEN1,RB1,XIAP,AR,BIRC2,BIRC3,BIRC5,BIRC7,CASP10,CASP2,CASP7,CAST,CDC42,CFLAR,CLSPN,CTSG,DCTN1,DFFA,DSP,EIF2AK2,GOLGA3,GORASP1,GZMB,HSPA5,KRT18,LYN,MAPT,MAX,MEF2A,MEF2D,NEDD4,PRKCZ,PSEN1,PSEN2,PSIP1,PSME3,PTMA,RAC1,RAD21,
Protein Size: 336 -
Molecular Weight
- 37 kDa
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Gene ID
- 840
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NCBI Accession
- NM_033338, NP_203124
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UniProt
- P55210
Target
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