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Caveolin 3 (CAV3) Peptide

CAV3 Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN974490

Quick Overview for Caveolin 3 (CAV3) Peptide (ABIN974490)

Target

Caveolin 3 (CAV3)

Origin

Human

Source

  • 2
Synthetic

Application

Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-CAV3 antibody (Catalog #: AVARP09021_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    Caveolin 3 (CAV3)

    Background

    CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

    Alias Symbols: LQT9, VIP21, LGMD1C, VIP-21

    Protein Interaction Partner: DAG1,DYSF,EGFR,GNAS,INSR,JPH2,NOS1,PFKM,SLC22A11,SLC8A1,DAG1,DYSF,EGFR,JPH2,PDGFRA,PDGFRB,PFKM,SLC8A1

    Protein Size: 151

    Molecular Weight

    17 kDa

    Gene ID

    859

    NCBI Accession

    NM_001234, NP_001225

    UniProt

    P56539
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