Pseudouridylate Synthase 10 (PUS10) (Middle Region) Peptide
PUS10
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974538
Quick Overview for Pseudouridylate Synthase 10 (PUS10) (Middle Region) Peptide (ABIN974538)
Target
PUS10
(Pseudouridylate Synthase 10 (PUS10))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- AVFVAGRYNK YSRNLPQTPW IIDGERKLES SVEELISDHL LAVFKAESFN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CCDC139 Antibody(ARP52750_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PUS10 (Pseudouridylate Synthase 10 (PUS10))
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Background
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Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).
Alias Symbols: FLJ32312, MGC126729, MGC126755, DOBI, CCDC139
Protein Size: 529 -
Molecular Weight
- 60 kDa
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Gene ID
- 150962
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NCBI Accession
- NM_144709, NP_653310
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UniProt
- Q3MIT2
Target
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