CD27 Molecule (CD27) (C-Term) Peptide
CD27
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974660
Quick Overview for CD27 Molecule (CD27) (C-Term) Peptide (ABIN974660)
Target
CD27
(CD27 Molecule (CD27))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LHQRRKYRSN KGESPVEPAE PCRYSCPREE EGSTIPIQED YRKPEPACSP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CD27 Antibody(ARP59093_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CD27 (CD27 Molecule (CD27))
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Background
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Alias Symbols: MGC20393, S152, T14, TNFRSF7, Tp55
Protein Interaction Partner: CD70,SIVA1,TRAF2,TRAF3,TRAF5,CD5,SIVA1,TRAF1,TRAF2,TRAF3,TRAF5
Protein Size: 260 -
Molecular Weight
- 27 kDa
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Gene ID
- 939
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NCBI Accession
- NM_001242, NP_001233
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UniProt
- P26842
Target
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