CD3 epsilon (CD3E) (Middle Region) Peptide
CD3E
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974673
Quick Overview for CD3 epsilon (CD3E) (Middle Region) Peptide (ABIN974673)
Target
CD3 epsilon (CD3E)
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- QYPGSEILWQ HNDKNIGGDE DDKNIGSDED HLSLKEFSEL EQSGYYVCYP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CD3E Antibody(ARP59097_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CD3 epsilon (CD3E)
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Background
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The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Alias Symbols: FLJ18683, T3E, TCRE
Protein Interaction Partner: CD3D,CD3EAP,CD3G,CD79B,LCK,NCK1,NCK2,NCL,PIK3R1,PTPN22,SHC1,SYK,TOP2B,TRAT1,UNC119,ZAP70,CD3EAP,CD3G,JAK3,NCK1,NCK2,NCL,PIK3R1,SYK,TOP2B,ZAP70
Protein Size: 207 -
Molecular Weight
- 23 kDa
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Gene ID
- 916
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NCBI Accession
- NM_000733, NP_000724
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UniProt
- P07766
Target
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