CD4 (CD4) (C-Term) Peptide
CD4
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974674
Quick Overview for CD4 (CD4) (C-Term) Peptide (ABIN974674)
Target
CD4
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- VLGGVAGLLL FIGLGIFFCV RCRHRRRQAE RMSQIKRLLS EKKTCQCPHR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CD4 Antibody(ARP59105_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CD4
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Background
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This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Alias Symbols: CD4mut
Protein Interaction Partner: CD4,env,CCR5,CD2,CD28,CD38,CD4,CD44,CD5,CD53,CD82,CTSD,CXCL12,CXCR4,DPP4,FCGR3A,HLA-DPA1,HLA-DQA2,HLA-DQB1,IL16,IL2RA,KCNAB2,LAT,LCK,LGALS1,MARCH4,PI4KA,PIK3R1,PIP,PTPRC,SELL,SPG21,TFRC,TNFRSF10A,UNC119,BTRC,CCR5,CD81,CD82,CXCR4,EPS15,IL16,KCNAB2,LCK,LGAL
Protein Size: 458 -
Molecular Weight
- 48 kDa
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Gene ID
- 920
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NCBI Accession
- NM_000616, NP_000607
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UniProt
- P01730
Target
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