CD44 (CD44) (C-Term) Peptide
CD44
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN974678
Quick Overview for CD44 (CD44) (C-Term) Peptide (ABIN974678)
Target
CD44
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- SGNGAVEDRK PSGLNGEASK SQEMVHLVNK ESSETPDQFM TADETRNLQN
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CD44 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CD44
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Background
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The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined.
Alias Symbols: CDW44, CSPG8, ECMR-III, HCELL, IN, LHR, MC56, MDU2, MDU3, MGC10468, MIC4, MUTCH-I, Pgp1, HUTCH-I
Protein Interaction Partner: EGFR,ANK1,ARHGEF1,ARHGEF12,CD4,CD44,CD74,COL14A1,COL1A1,COL1A2,CSK,DMP1,EGFR,EPB41,ERBB4,EZR,FGF2,FYN,GARS,HBEGF,HMMR,IGFBP3,LCK,MADCAM1,MMP1,MMP7,MMP9,NF2,PKN1,SELE,SPP1,SRGN,TGFBR1,TGFBR2,TIAM1,VAV2,VCAN,ARHGEF1,COL14A1,EGFR,EPB41L3,ERBB2,ERBB4,EZR,FN1,
Protein Size: 361 -
Molecular Weight
- 40 kDa
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Gene ID
- 960
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NCBI Accession
- NM_001001391, NP_001001391
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UniProt
- P16070
Target
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