Cyclin-Dependent Kinase 1 (CDK1) Peptide
CDK1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN974712
Quick Overview for Cyclin-Dependent Kinase 1 (CDK1) Peptide (ABIN974712)
Target
CDK1
(Cyclin-Dependent Kinase 1 (CDK1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CDC2 antibody (Catalog #: AVARP03024_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
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Background
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The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Alias Symbols: CDC28A, CDK1, DKFZp686L20222, MGC111195, CDC2, P34CDC2
Protein Interaction Partner: E2F1,E2F3,E2F4,E2F4,E2F4,NRF1,CCNA1,CCNA2,CCNB1,CCNB1,CCNB1,CCNB2,CCNB2,CDKN1A,MDM4,PITPNM1,PKMYT1,WEE1,ABL1,AMPH,APLP2,AR,BIRC5,BRCA1,BRCA2,BUB1,C13orf15,CALD1,CCNA1,CCNA2,CCNB1,CCNB2,CCNE1,CDC25A,CDC25B,CDC25C,CDK1,CDK7,CDKN1A,CDKN3,CDT1,CEP55,CHAF1B,CKS2,CNOT7,CREM,CSNK2A1,CSNK2B,CUX1,DAB2,DNM2,DUT,E2F1,ECT2,EEF1D,EPN1,ERCC2,FANCA,FANCC,FANCG,FEN1,FOXM1,FYN,GADD45A,GADD45B,GADD45G,GFAP,GOLGA2,GORASP1,HMGA1,HMGA2,HSPA2,IL16,ITPR1,KAT5,KHDRBS1,KIF11,KIF20B,KRT18,LATS1,LMNA,LMNB1,LYN,LZTS1,MAP4,MAPT,MCM4,MDM4,MEF2C,MNDA,MYC,MYT1,NDE1,NES,NPM1,NSFL1C,NUP210,PBK,PCNA,PIN1,PITPNM1,PKMYT1,PLEC,POLA1,PPP2R1A,PPP2R1B,PTCH1,PTMA,PTPN1,PTPN2,PTTG1,RAB4A,RAB5B,RAP1GAP,RB1,RCC1,RPA2,RPS6KB1,RRM2,RUNX2,SFN,SPAG5,STMN1,STMN2,TGFBR2,TK1,TLE1,TOP2A,TP53,TP73,TSC1,UBA1,UBE2A,USP16,VIM,WEE1,ZBTB16,BCL2,BRCA1,CCNA1,CCNA2,CCNA2,CCNB1,CCNB1,CCNB1,CCNB1,CCNE1,CCNF,CDC25C,CDKN1A,CDKN3,CIITA,CNOT7,CUX1,DAB2,ESPL1,FANCA,FANCC,FANCG,FEN1,FYN,GADD45A,GADD45A,GADD45B,GADD45B,GADD45G,GADD45G,HIST1H1A,HMGB1,HSPA4,LATS1,LYN,LZTS1,MAP4,MKI67,NSFL1C,PRKCB,SFN,SPAG5,TP53,TSC1,UBC,UIMC1,USP19,USP32,USP45,ZBTB16
Protein Size: 297 -
Molecular Weight
- 34 kDa
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Gene ID
- 983
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NCBI Accession
- NM_001786, NP_001777
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UniProt
- P06493
Target
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