Cell Division Cycle 23 (CDC23) Peptide
CDC23
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CDC23 products
- CDC23 (Cell Division Cycle 23 (CDC23))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CDC23 antibody (Catalog #: ARP43039_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CDC23 (Cell Division Cycle 23 (CDC23))
- Background
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CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
Alias Symbols: APC8, CUT23, ANAPC8
Protein Interaction Partner: ANAPC10,CDC16,RAD54B,RBPMS,TSC22D4,ANAPC1,ANAPC4,APC2,CDC20,CDC27,CDH1,CDT1,RAD54B,RBPMS,TSC22D4
Protein Size: 597 - Molecular Weight
- 66 kDa
- Gene ID
- 8697
- NCBI Accession
- NM_004661, NP_004652
- UniProt
- Q9UJX2
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