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Cyclin-Dependent Kinase 7 (CDK7) Peptide

CDK7 Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN974778

Quick Overview for Cyclin-Dependent Kinase 7 (CDK7) Peptide (ABIN974778)

Target

CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Origin

Human

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-CDK7 antibody (Catalog #: AVARP03009_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

    Background

    Cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcripti

    Alias Symbols: CAK1, CDKN7, MO15, STK1, p39MO15, HCAK

    Protein Interaction Partner: CDK2,CDK6,RARA,THRA,VDR,AR,BRCA1,CCNH,CDK1,CDK2,CDK7,E2F1,ERCC2,ERCC3,ESR1,GTF2H1,GTF2H2,GTF2H5,LASP1,MCM7,MNAT1,NEK6,PCGF6,RARA,THRA,VDR,AR,CCNH,CCT2,CDC37,CUX1,E2F1,ERCC3,ERCC5,ESR1,GTF2H1,GTF2H2,GTF2H3,GTF2H4,GTF2H5,HDAC2,HNRNPU,HSP90AB1,KIAA1967,MCM7,MED21,MNAT1,MTA1,POLR2A,RUVBL2,SUPT5H,TCEA1,TP53

    Protein Size: 346

    Molecular Weight

    39 kDa

    Gene ID

    1022

    NCBI Accession

    NM_001799, NP_001790

    UniProt

    P50613
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